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EC number: 943-330-9 | CAS number: -
For detailed information on the results please refer to the attached report.
Readily biodegradable: 74 - 82% in 28 days (OECD 301B); read across;
QSAR prediction: readily biodegradable.
Experimental data on the biodegradability of the target substance Reaction mass of bis[2-[2-(2-butoxyethoxy)ethoxy]ethyl] adipate and [2-[2-(2-butoxyethoxy)ethoxy]ethyl](3,6,9,12-tetraoxahexadecyl)adipate (EC 943-330-9) are not available. The assessment was therefore based on studies conducted with the analogue substance Bis(2-(2-butoxyethoxy)ethyl) adipate (CAS 141-17-3) and on QSAR calculations performed with the main substance components. The read across approach is in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Please see the analogue justification attached to IUCLID section 13 for a detailed justification.
The biodegradability of the source substance Bis(2-(2-butoxyethoxy)ethyl) adipate (CAS 141-17-3) was tested according to OECD 301B under GLP conditions using non-adapted activated sludge as inoculum. The degradation rate was tested with two different test substance concentrations i.e. 10 mg and 20 mg test material/L. After 28 days a mean degradation rate of 74 % was observed at a test substance concentration of 10 mg/L). The observed degradation rate at 20 mg/L was 82% after 28 days. The 10-day-window was met and the substance was considered as readily biodegradable according to OECD criteria.
The read across approach is supported by QSAR calculations performed with two main substance components of the target substance. Ready biodegradability was predicted for both substance components (VEGA 1.1.4, Ready biodegradability model v1.0.9).
Based on the results for the source substance (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5), as well as on the results of the QSAR calculation, Reaction mass of bis[2-[2-(2-butoxyethoxy)ethoxy]ethyl] adipate and [2-[2-(2-butoxyethoxy)ethoxy]ethyl](3,6,9,12-tetraoxahexadecyl)adipate (EC 943-330-9) is considered as readily biodegradable.
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