Registration Dossier

Ecotoxicological information

Toxicity to microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

EC50 (3 h) > 1000 mg/l (nominal, act. ingr.)

Key value for chemical safety assessment

EC50 for microorganisms:
1 000 mg/L

Additional information

The determination of the inhibition of oxygen consumption in the activated sludge was performed in a 3-hours test with the CAS 13863 -31 -5, according to the OECD guideline 209. The concentration tested were 1000, 500, 250, 125, 62.5 mg/l based on active ingredient of the test substance, which equate to a nominal test concentration of 1333, 667, 333, 167 and 83.3 mg/l. The EC50 at 3 hours was stated as greater than 1000 mg/l (nominal, act. ingr.) (BASF SE, 2015).

Three further studies on the analogue substance CAS 4193-55-9 are available in order to assess the toxicity of the substance to microorganisms, but each of them presents some lacking: in two of them a water solution with 20 % of the substance was tested and for the third one just the summary is available.

The RCC - Umweltchemie GmbH & Co. study (1993) can be considered as the most reliable, since even if the tested substance concentration is low, the test was performed at 1000 mg/l, with no inhibitory effect. This set the result at > 200 mg/l, calculated on the substance effective concentration.

As a supporting study a reliable test performed on the similar substance CAS 16470-24-9, was also reported. Detailed justification for Read Across is reported within the endpoint and in the category Justification Report attached to section 13 of this dossier.