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Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1988
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1988
Report date:
1988

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 420 (Acute Oral Toxicity - Fixed Dose Method)
GLP compliance:
not specified
Test type:
fixed dose procedure

Test material

Constituent 1
Chemical structure
Reference substance name:
Jojoba, ext., hydrogenated
EC Number:
296-292-4
EC Name:
Jojoba, ext., hydrogenated
Cas Number:
92457-12-0
Molecular formula:
No molecular formula is available since it is a UVCB substance
IUPAC Name:
Jojoba, ext., hydrogenated
Test material form:
solid: flakes

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female
Details on test animals or test system and environmental conditions:
TEST ANIMALS
- 5 male and 5 female

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
corn oil
Details on oral exposure:
single dose administered 5 000 g/kg; 50% in corn oil to rats after 18h of fasting
Doses:
5 g/kg; 50% in corn oil
No. of animals per sex per dose:
5 male and 5 female

Results and discussion

Effect levels
Key result
Sex:
male/female
Dose descriptor:
LD50
Effect level:
>= 5 000 mg/kg bw
Based on:
test mat. (dissolved fraction)
Mortality:
none
Clinical signs:
none

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
The test material as submitted, when tested as described above is not classified as toxic