Jojoba, ext., hydrogenated

Acute Toxicity: oral

Administrative data

Endpoint:

acute toxicity: oral

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1988

Reliability:

2 (reliable with restrictions)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1988

Report date:

1988

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 420 (Acute Oral Toxicity - Fixed Dose Method)

GLP compliance:

not specified

Test type:

fixed dose procedure

Test material

Test material information

Constituent 1

Reference substance name:

Jojoba, ext., hydrogenated

EC Number:

296-292-4

EC Name:

Jojoba, ext., hydrogenated

Cas Number:

92457-12-0

Molecular formula:

No molecular formula is available since it is a UVCB substance

IUPAC Name:

Jojoba (Simmondsia Chinensis) Seed Oil Hydrogenated

Test material form:

solid: flakes

Test animals

Species:

rat

Strain:

Sprague-Dawley

Sex:

male/female

Details on test animals or test system and environmental conditions:

TEST ANIMALS
- 5 male and 5 female

Administration / exposure

Route of administration:

oral: unspecified

Vehicle:

corn oil

Details on oral exposure:

single dose administered 5 000 g/kg; 50% in corn oil to rats after 18h of fasting

Doses:

5 g/kg; 50% in corn oil

No. of animals per sex per dose:

5 male and 5 female

Results and discussion

Effect levels

Key result

Sex:

male/female

Dose descriptor:

LD50

Effect level:

>= 5 000 mg/kg bw

Based on:

test mat. (dissolved fraction)

Mortality:

none

Clinical signs:

other: none

Applicant's summary and conclusion

Interpretation of results:

GHS criteria not met

Conclusions:

The test material as submitted, when tested as described above is not classified as toxic