Registration Dossier
Registration Dossier
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EC number: 910-356-7 | CAS number: -
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
According to REACH Annex VIII there is no data requirement for bioaccumulation in aquatic organisms. However, a BCF was requisite in order to fulfil the input data requirements that were necessary to perform the exposure assessment in Chesar. A BCF of 600 (for fish, upper end) was used because very low bioconcentration or bioaccumulation in aquatic organisms was anticipated (see additional information below).
Key value for chemical safety assessment
- BCF (aquatic species):
- 600 dimensionless
Additional information
According to the evaluation of the EU assessment report on copper oxide (Directive 98/8/EC concerning the placing of biocidal products on the market, Copper (II) oxide, 2011, France), bioaccumulation and biomagnification did not apply for the constituent copper oxide of the submission substance, because bioavailable copper was an essential micronutrient and molecular mechanism of copper homeostasis exist in organisms.
For the constituent manganese dioxide, the OECD SIDS report on manganese dioxide (NIER, Republic of Korea, 2007) reported that manganese significantly bioconcentrated in lower organisms, e.g. marine plants (10-20000) and invertebrates (10-40,000), but showed small bioconcentration in fish (100-600), indicating that manganese has very low potential to accumulated in the food chain (Manganese and its compounds, International Programme on Chemical Safety (Concise International Chemical Assessment Document 63), WHO, Geneva, Switzerland).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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