Reaction mass of copper oxide and manganese dioxide

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017-02-14

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)

Version / remarks:

adopted May 1981

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: DIN 66165 part 1 and 2: Sieving analysis

Version / remarks:

2016-08

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: Guidance on information requirements and chemical safety assessment, Chapter R.7a: Endpoint specific guidance, European Chemicals Agency

Version / remarks:

version 4.1, October 2015

GLP compliance:

yes (incl. QA statement)

Type of method:

sieving

Type of particle tested:

primary particle

Type of distribution:

mass based distribution

Specific details on test material used for the study:

The test item was tested as received. No further preliminary treatment such as drying or milling was performed.

Remarks on result:

not determinable

Remarks:

Due to the large size of the particles (99.54% by mass >500 µm by sieving), sieving was the method chosen. No MMAD can be determined from sieving - however, based on the large particle size there will be no relevant inhalable fraction.

Key result

Percentile:

D10

Mean:

1 100 µm

Remarks on result:

other: Range of particle size for mesh size 1000 µm: 1000 µm to 1250 µm

Percentile:

D50

Mean:

1 300 µm

Remarks on result:

other: Range of particle size for mesh size 1250 µm: 1250 µm to 1400 µm

Percentile:

D90

Mean:

1 500 µm

Remarks on result:

other: Range of particle size for mesh size 1400 µm: 1400 µm to 1600 µm

The test item consisted of granules (approximately 1 to 2 mm in diameter). Due to the size of the granules the particle size distribution was determined by dry sieving.

242.08 g of the test item were placed on the top sieve. After closing the sieve stack and placing it into the sieving machine sieving was performed for 5 min with amplitude of 1.5 mm. The particle size is shown in the following table:

Mesh size	Range of particle size	Fraction	Total	Fraction	Total
µm	µm	g	g	%	%
2000	> 2000	0.00	0.00	0.00	0.00
1700	1700 – 2000	0.05	0.05	0.02	0.02
1600	1600 – 1700	1.90	1.95	0.78	0.81
1400	1400 – 1600	54.43	56.38	22.48	23.29
1250	1250 – 1400	125.87	182.25	52.00	75.29
1000	1000 – 1250	56.79	239.04	23.46	98.74
800	800 – 1000	1.62	240.66	0.67	99.41
500	500 – 800	0.31	240.97	0.13	99.54
300	300 – 500	0.11	241.08	0.05	99.59
250	250 - 300	0.08	241.16	0.03	99.62
Receiver pan	0 – 250	0.92	242.08	0.38	100.00

The percentiles of the particle size distribution were estimated from cumulative plotting of the size fraction (by mass) given in the table above against the mesh size (µm) on the abscissa.

The particle size D₅₀estimated from this measurement was:

D₅₀= 1300 µm

The particle size D₁₀estimated from this measurement was:

D₁₀= 1100 µm

The particle size D₉₀estimated from this measurement was:

D₉₀= 1500 µm

Conclusions:

Due to the large size of the particles (99.54% by mass >500 µm by sieving), sieving was the method chosen. No MMAD can be determined from sieving - however, based on the large particle size there will be no relevant inhalable fraction:
D50 = 1300 µm
D10 = 1100 µm
D90 = 1500 µm

Executive summary:

The particle size distribution was determined for the submission substance according to OECD 110 and DIN 66165 part 1 and 2: Sieving analysis, under consideration of ECHA guidance document R.7a. The test item consisted of granules (approximately 1 to 2 mm in diameter). Due to the size of the granules the particle size distribution was determined by dry sieving. No MMAD can be determined from sieving - however, based on the large particle size there will be no relevant inhalable fraction.

The percentiles of the particle size distribution were estimated from cumulative plotting of the size fraction (by mass) against the mesh size (µm) on the abscissa.

The particle size D₅₀estimated from this measurement was:

D₅₀= 1300 µm

The particle size D₁₀estimated from this measurement was:

D₁₀= 1100 µm

The particle size D₉₀estimated from this measurement was:

D₉₀= 1500 µm

Description of key information

Due to the large size of the particles (99.54% by mass >500 µm by sieving), sieving was the method chosen (OECD 110, DIN66165 part 1 and 2: sieving analysis; RL1, 2017). No MMAD can be determined from sieving - however, based on the large particle size there will be no relevant inhalable fraction:

D50 = 1300 µm

D10 = 1100 µm

D90 = 1500 µm

Additional information

The particle size distribution was determined for the submission substance according to OECD 110 and DIN 66165 part 1 and 2: Sieving analysis, under consideration of ECHA guidance document R.7a. The test item consisted of granules (approximately 1 to 2 mm in diameter). Due to the size of the granules the particle size distribution was determined by dry sieving. No MMAD can be determined from sieving - however, based on the large particle size there will be no relevant inhalable fraction.

The percentiles of the particle size distribution were estimated from cumulative plotting of the size fraction (by mass) against the mesh size (µm) on the abscissa.

The particle size D₅₀estimated from this measurement was:

D₅₀= 1300 µm

The particle size D₁₀estimated from this measurement was:

D₁₀= 1100 µm

The particle size D₉₀estimated from this measurement was:

D₉₀= 1500 µm