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Administrative data

Endpoint:
sediment toxicity: long-term
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
data waiving: supporting information
Reference

No acute aquatic toxicity to fish study for magnesium silicate available.  Read-across from silicon dioxide and sodium aluminium silicate (NAS) studies show a low acute toxicity.

Reason / purpose for cross-reference:
data waiving: supporting information
Reference

No acute toxicity data on daphnia for magnesium silicate available, however, based on read-across from silicon dioxide it is expected to shows no acute toxicity with an EL50 >10,000 mg/L (effective loading).  

Effect concentration:
10 000 mg/L

Based on the high tolerance and ubiquitous natural occurrence of this substance class, the need for generation of data for this specific compound is waived in line with REACH Regulation 1907/2006, Annex IX, Section 9.1.

There was no adverse effect on daphniae in the presence of water-accommodated fractions ofstructure-analogous synthetic amorphous silica (SAS). Therefore, it is concluded that magnesium silicate will

also not be toxic to daphnia.

It is assumed that the freshwater results are also applicable to marine life, i.e. no acute aquatic toxicity expected from exposure to magnesium silicate.

Reason / purpose for cross-reference:
data waiving: supporting information
Reference

A structure-analogous silicate failed to produce any aquatic toxicity, EL50 >10,000 mg/L. Based on the high tolerance and ubiquitous natural occurrence of this substance class, the need for generation of data for this specific compound is waived in line with REACH Regulation 1907/2006, Annex IX, Section 9.1.

EC50 for freshwater algae:
10 000 mg/L
EC10 or NOEC for freshwater algae:
10 000 mg/L

No acute and chronic aquatic toxicity - including the marine environment - expected from exposure to magnesium silicate.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion