Reaction mass of 4-sulfophthalic acid and 3-sulfophthalic acid

Endpoint summary

Description of key information

There are no short-term toxicity to fish, aquatic invertebrates adn algae studies on the reaction mass of 4-sulphophthalic acid and 3-sulphophthalic acid (read across target substance). However, short-term toxicity to fish, aquatic invertebrates, and algae data are available for the reaction mass of 1,2-benzenedicarboxylic acid, 4-sulfo-, trisodium salt, 1,2-benzenedicarboxylic acid, 3-sulfo-, sodium salt (1:3), sodium sulphate (read across source substance) and it was used for read-across purposes.

In a 96-hour acute toxicity study, Golden Orfe (Leuciscus Idus L., Golden Variety) were exposed to nominal concentrations of 0 and 10,000 mg/L WAF (water-accommodated fractions) under static renewal conditions. The 96-hour LL50 (loading rate of test substance resulting 50% mortality) was >10,000 mg/L nominal WAF. No signs of toxicity were noted.

The acute toxicity of the source substance on the aquatic invertebrate Daphnia magna was studied under static conditions. Daphnids were exposed to control and test chemical at nominal concentrations of 100, 300, and 1000 mg/L WAF for 48 hours. Mortality, immobilisation and sub-lethal effects were observed daily. The 48 hr-EC₀, EC₅₀, EC₁₀₀were 62.5, 88.39 and 125 mg/L, respectively.

In a 72-hour toxicity study, the cultures of the green algae (Desmodesmus subspicatus) were exposed at nominal concentrations of 0 and 100 mg/L nominal WAF loading rate under static in accordance with the guideline OECD Guideline 201 (Alga, Growth Inhibition Test). There were no compound related phytotoxic effects, and the 72-hr EC50was determined to be 90.8 mg/L.