Registration Dossier
Registration Dossier
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EC number: 216-381-3 | CAS number: 1570-64-5
Endpoint summary
Administrative data
Description of key information
Additional information
Summary of the aquatic toxicity end points.
| End Point | Organism | Toxicity | Reference |
| Acute tox. Aquatic invertebrates | Daphnia Magna | EC50 (48h,static) 1.0 mg/L | BASF |
| Chronic Tox. Aquatic invertebrates | Daphnia magna | EC50 (48h,static) >0.56 mg/L | Brixham Environmental Laboraotry |
| Toxicity to Algae and Cyanobacteria | Scenedesmus subspicatus (Desmodesmus subspicatus) | EbC50 (72h,static) 14.81mg/L | BASF |
| Toxicity to Microorganisms | Pseudomonas putida | EC50(17h) 110mg/L | BASF |
| Toxicity to Aquatic Plants | Lemna Minor | EC50 (7 day,biomass) 15.7 mg/L | Chemex Environmental International Limited |
Additional toxicity data on other aquatic compartments is available in the published Danish Review document. Although the additional data is not a requirement for a transported isolated intermediate, the document is attached under section 13 for reference.
Based on the endpoint values summarised above the lowest acute value is for Daphnia magna. The value of 1.0 mg/L for the acute study places 4-chloro-2 -methylphenol in 'acute category 1' under GHS regulations and 'R50' category under DSD-DPD regulations. The threshold for both classifications being <= 1mg/L 48 hour EC50 (daphnia/crustacea).
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