Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
other: no data
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
US Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals
Year:
1994
Bibliographic source:
cited in: RTECS April, 1994

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Butyl isocyanate
EC Number:
203-862-8
EC Name:
Butyl isocyanate
Cas Number:
111-36-4
Molecular formula:
C5H9NO
IUPAC Name:
1-isocyanatobutane
Details on test material:
IUCLID4 Test substance: other TS: n-butyl isocyanate, no data on purity

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intravenous
Vehicle:
not specified
Details on exposure:
no data
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified
Statistics:
no data

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
1 mg/kg bw
Mortality:
no data
Clinical signs:
no data
Body weight:
no data
Gross pathology:
no data
Other findings:
no data

Applicant's summary and conclusion