Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

Currently viewing:

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary literature

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1972

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified
Test type:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
Butyl isocyanate
EC Number:
203-862-8
EC Name:
Butyl isocyanate
Cas Number:
111-36-4
Molecular formula:
C5H9NO
IUPAC Name:
1-isocyanatobutane
Details on test material:
IUCLID4 Test substance: other TS: n-butyl isocyanate, no data on purity

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Duration of exposure:
no data
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified
Statistics:
no data

Results and discussion

Effect levels
Dose descriptor:
other: ALD
Effect level:
700 mg/kg bw
Mortality:
no data
Clinical signs:
no data
Body weight:
no data
Gross pathology:
no data
Other findings:
no data

Applicant's summary and conclusion