Registration Dossier
Registration Dossier
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EC number: 203-862-8 | CAS number: 111-36-4
Toxicity to terrestrial plants
Administrative data
- Endpoint:
- toxicity to terrestrial plants
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study meets generally accepted scientific principles
Data source
Reference
- Reference Type:
- publication
- Title:
- N,N'-dibutylurea from n-butyl isocyanate, a degradation product of benomyl. 1. Formation in benlate formulations and on plants. J
- Author:
- Moye HA, Shilling DG, Aldrich HC, Gander JE, Buszko M, Toth JP, Brey WS, Bechtel B, Tolson JK (1994).
- Year:
- 1 994
- Bibliographic source:
- Agric. Food Chem. 42, 1204-1208.
Materials and methods
- Principles of method if other than guideline:
- Method: other: Phytotoxicity test method developed by the authors (Moye et al., 1994)
- GLP compliance:
- no
Test material
- Reference substance name:
- Butyl isocyanate
- EC Number:
- 203-862-8
- EC Name:
- Butyl isocyanate
- Cas Number:
- 111-36-4
- Molecular formula:
- C5H9NO
- IUPAC Name:
- 1-isocyanatobutane
- Details on test material:
- IUCLID4 Test substance: other TS: n-Butyl isocyanate, purity > 99 %
Constituent 1
Test organisms
- Species:
- other: other terrestrial plant: fern (Nephrolepis exaltata) and cucumber (Cucumis sativus L.)
Results and discussion
Any other information on results incl. tables
RS-Freetext:
After 24 h both sets of plants showed phytotoxic symptoms.
Dibutylurea was detected in extracts of all treated plants.
Whether the plant phytotoxicity was due to n-butyl
isocyanate or its hydrolysis products dibutylurea or
butylamine was not analyzed.
The following observations were made:
FERN:
- After 24 h the ferns showed brown spots on the leaves
- After 72 h they were totally brown and died off
CUCUMBER:
- After 24 h spotted browning of the cotyledons followed by
a browning of the guttation water
- By 72 h browning to the mature leaves had increased but
had not covered the entire leaves
- After 72 h the mature leaves exhibited intravenal
yellowing and a yellowing around the edges
Applicant's summary and conclusion
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