Registration Dossier

Physical & Chemical properties

Melting point / freezing point

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
2009-04-21
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
The study was conducted according to an OECD test guideline and in accordance with a recognised quality system
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
GLP compliance:
no
Other quality assurance:
other: ISO 9001
Type of method:
differential scanning calorimetry
Key result
Melting / freezing pt.:
< -50 °C
Atm. press.:
1 013 hPa
Decomposition:
no

No definite melting temperature was detected between -150°C and 25°C but only a phase transition similar to glass transition at –140.5°C (132.7 K) was observed.

Approximate accuracy of the instrument: ± 0.5 K (up to 600 K)

Conclusions:
A melting point value of <-50°C at 1013 hPa was determined for the substance in a reliable study conducted according to OECD Guideline 102, the result is considered reliable.
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
2015-07-07
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
The study was conducted according to a relevant test method and in accordance with a recognised quality system
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
GLP compliance:
no
Other quality assurance:
other: ISO 9001:2008
Type of method:
differential scanning calorimetry
Key result
Melting / freezing pt.:
< -100 °C
Atm. press.:
1 013 hPa
Decomposition:
no

The DSC diagrams showed no melting/freezing temperature above –100°C, see attached DSC thermograms. The results are shown in Table 1

Table 1: Results

Test

Melting- / Freezing temperature

1

< –100°C

2

< –100°C

Mean value:

< –100°C, < 173 K

Approximate accuracy of the instrument: ± 0.5 K (up to 600K)

Conclusions:
A melting point value of <-100°C at 1013 hPa was determined for the substance in a reliable study conducted according to a relevant test method and in compliance with a known quality system. The result is considered to be reliable.

Description of key information

Melting point: <-20°C at 1013 hPa (OECD 102)

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
-20 °C

Additional information

There are two reliable measured melting/freezing point studies available for the registered substance. In the first study (Haas 2009), a melting point value of <-50°C at 1013 hPa was determined for the substance using a Differential Scanning Calorimetry (DSC) method in accordance with OECD Test Guideline 102. There was no clear and definite melting temperature between –150°C and +25°C but only a phase transition which was similar to a glass transition at –140.5°C was observed. The melting/freezing temperature was therefore concluded to be <–50°C. Similarly, in the second study (Haas 2015), no melting/freezing temperature above -100°C was determined using a DSC method in accordance with a relevant test method and in compliance with a known quality system (ISO 9001:2008). Both results indicate that the melting/freezing temperature of the registered substance is <-20°C at 1013 hPa. The results are therefore considered to be reliable and are used as weight of evidence.