Registration Dossier

Administrative data

Description of key information

Triethoxy (2,4,4-trimethylpentyl)silane was not sensitising in a guinea pig maximisation test carried out in accordance with OECD 406 and in compliance with GLP (BSL Bioservice, 2001c). No positive skin reactions were observed.

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

The key sensitisation study is the only available study for this endpoint. This was a reliable, guideline study, conducted in accordance with GLP.

Justification for classification or non-classification

Based on the available data, no classification is proposed for sensitisation in accordance with Regulation (EC) No. 1272/2008.