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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: No data on GLP and OECD guidelines compliance

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
Bingham, E.; Cohrssen, B.; Powell, C.H.
Year:
2001
Bibliographic source:
Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. 4:1330

Materials and methods

Principles of method if other than guideline:
No data.
GLP compliance:
not specified
Test type:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
2,4,6-trichloro-1,3,5-triazine
EC Number:
203-614-9
EC Name:
2,4,6-trichloro-1,3,5-triazine
Cas Number:
108-77-0
Molecular formula:
C3Cl3N3
IUPAC Name:
2,4,6-trichloro-1,3,5-triazine

Test animals

Species:
rat
Sex:
not specified

Administration / exposure

Route of administration:
inhalation: dust
Type of inhalation exposure:
not specified
Vehicle:
not specified
Analytical verification of test atmosphere concentrations:
not specified
Concentrations:
No data.
No. of animals per sex per dose:
No data.
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
25 mg/m³ air
Based on:
test mat.
Exp. duration:
4 h

Applicant's summary and conclusion

Conclusions:
4 h-LC50: 25 mg/m³ air
Executive summary:

The acute exposure in an inhalation study with the dust (cyanuric chloride) has shown that 4h-LC50 is rats is 25 mg/m³ (20.4% respirable particles, less than 10 mcm in diameter).