Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Inhalation:
NOAEC = 0.25 mg/m3 for systemic toxicity.
NOAEC = 0.05 mg/m3f or local effects.

Key value for chemical safety assessment

Repeated dose toxicity: inhalation - systemic effects

Endpoint conclusion
Dose descriptor:
NOAEC
0.25 mg/m³
Study duration:
subchronic
Species:
rat

Additional information

The repeated dose toxicity by inhalation was stated in one study according to OECD Guideline 413 and 84/449/EEC, and the NOAEC results were the following:

NOAEC = 0.25 mg/m3for systemic toxicity

NOAEC = 0.05 mg/m3for local effects

Justification for classification or non-classification