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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient)
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
3.25
Temp.:
40 °C
pH:
7

Log Pow was determined at 40 °C (HPLC column temperature, 101.3 kPa assumed).

Conclusions:
Under the conditions of this study the Log Pow of the test item is 3.25.

Description of key information

The partition coefficient was determined by application of EC Method A8/OECD 117. 

Key value for chemical safety assessment

Log Kow (Log Pow):
3.25
at the temperature of:
40 °C

Additional information

The log Kow of the test item is 3.25, determined at 40 °C (HPLC method).