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Short-term toxicity to fish

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The conduct of an acute toxicity study on fish with the target substance titanium oxychloride itself is being waived, as the substance is highly unstable in water and produces insoluble oxide after rapid hydrolysis. Nevertheless, based on the information available it can be concluded that neither the parent compound titanium tetrachloride, nor the target compound titanium oxychloride nor the final hydrolysis transformation products (namely titanium dioxide) exhibit acute toxicity to fish.

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Titanium tetrachloride rapidly hydrolyses in water via titanium oxychloride, resulting in the formation of titanium dioxide (CAS 13463-67-7) and causing an increase in acidity. Titanium dioxide is very poorly soluble in water at neutral pH (< 0.1 μg/L); excess titanium dioxide will be present as insoluble matter. Aquatic toxicity data for the titanium dioxide in marine (Thomson 2007a) and freshwater (Hutton 1992) show the absence of short-term effects in fish at nominal concentrations that are several orders of magnitude higher than the soluble concentration plus additional load of undissolved microdisperse matter in excess. Physical effects on fish might occur as a result of fouling, smothering or coating with high loadings of titanium dioxide precipitate but these are not a consequence of the toxicity of the substance.

It is concluded that neither the target compound titanium oxychloride, nor parent compound titanium tetrachloride, nor the final hydrolysis transformation products titanium dioxide and hydrochloric acid (in its neutralised form) exhibit acute effects to fish at the level of their water solubility in addition with undissolved microdisperse matter in excess, even if ingested.

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