Registration Dossier

Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

"There are no experimental studies on the toxicokinetics of ethoxylated propylidyne trimethanol. The toxicokinetics of ethoxylated propylidyne trimethanol is inferred from the core substance and ethane-1,2-diol, oxydiethanol and (ethylenedioxy)diethanol. The toxicokinetics for these substances are summarised in Illing and Barratt (2007 revised 2009). Propylidyne trimethanol has three free hydroxy groups, thus NLP polyols are likely to consist predominantly of chains of between one and two repeating units, with some chains containing three repeating units. Commercial material contains a range of propoxylated propanediols" (Cited from Paul Illing Consultancy Services Ltd. and Marlin Consultancy, Grouping of NLP Additional NLP ‘Polyols’ and their Toxicokinetics Assessments, 2010).

 

Discussion on bioaccumulation potential result:

"There are no experimental studies on the toxicokinetics of ethoxylated propylidyne trimethanol. The toxicokinetics of ethoxylated propylidyne trimethanol is inferred from the core substance and ethane-1,2-diol, oxydiethanol and (ethylenedioxy)diethanol. The toxicokinetics for these substances are summarised in Illing and Barratt (2007 revised 2009). Propylidyne trimethanol has three free hydroxy groups, thus NLP polyols are likely to consist predominantly of chains of between one and two repeating units, with some chains containing three repeating units. Commercial material contains a range of propoxylated propanediols" (cited from Paul Illing Consultancy Services Ltd. and Marlin Consultancy, Grouping of NLP ‘Polyols’ and their Toxicokinetics Assessments).