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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

Measured EC20 (72hr) >500mg/l
QSAR: EC50 (96hr)=4975mg/l, NOEC=1068g/l
Surrogate substance (predicted to be more toxic): EC0 (96hr) =1000mg/l

Key value for chemical safety assessment

EC50 for freshwater algae:
4 975 mg/L
EC10 or NOEC for freshwater algae:
1 000 mg/L

Additional information

In a growth inhibition acute toxicity test, the green algae Scenedesmus subspicatus were exposed to concentrations of 2 -(2 -(2 -methoxyethoxy)ethoxy)ethanol at concentrations up to 500mg/l for a period of 72 hours. No growth inhibition was seen, indicating that the substance is practically non-toxic to algae. Whilst only an EC20 is quoted (>500mg/l), it is assumed based on information available in this and other studies that this would be the same as the EC10. This result is supported by information from the ECOSAR QSAR model, which predicts that the 96hr EC50 value for algae would be 4975mg/l and the 96hr NOEC 1068mg/l and from a surrogate substance predicted by the QSAR to be inherently more toxic which shows a NOEC of 1000mg/l . The QSAR result is used as a basis for the EC50 whilst the surrogate result is used as a basis for the EC10 supported by the results available from the experimental 'key' study.