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Physical & Chemical properties

Dissociation constant

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Reference
Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Peer-reviewed database
Principles of method if other than guideline:
Experimental determination
GLP compliance:
not specified
Dissociating properties:
yes
No.:
#1
pKa:
10.732
Temp.:
25 °C
Remarks on result:
other: Temperature value is an estimate as actual temperature value was not specified
Conclusions:
A pKa value of 10.73 is reported. A pKa of 10.73 indicates dimethylamine will exist almost entirely in the cation form at pH values of 5 to 9 and therefore volatilization from water surfaces and moist soil surfaces is not expected to be an important fate process
Executive summary:

A pKa value of 10.732 is reported. A pKa of 10.73 indicates dimethylamine will exist almost entirely in the cation form at pH values of 5 to 9 and therefore volatilization from water surfaces and moist soil surfaces is not expected to be an important fate process.

Description of key information

A pKa value of 10.73 is reported (HSDB, 2010). 

Key value for chemical safety assessment

pKa at 20°C:
10.73

Additional information

A pKa value of 10.73 is reported. This indicates dimethylamine will exist almost entirely in the cation form at pH values of 5 to 9 and therefore volatilization from water surfaces and moist soil surfaces is not expected to be an important fate process.