Ferrate(1-), [[N,N'-1,2-ethanediylbis[N-[[2-(hydroxy-.kappa.O)phenyl]methyl]glycinato-.kappa.N,.kappa.O]](4-)]-, sodium (1:1), (OC-6-13)-

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.071 mg/L

Assessment factor:

1 000

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

0.71 mg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0.007 mg/L

Assessment factor:

10 000

Extrapolation method:

assessment factor

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

10 mg/L

Assessment factor:

100

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

0.16 mg/kg sediment dw

Extrapolation method:

sensitivity distribution

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

0.016 mg/kg sediment dw

Extrapolation method:

sensitivity distribution

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

0.3 mg/kg soil dw

Assessment factor:

100

Extrapolation method:

assessment factor

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

PNEC oral

PNEC value:

2.22 mg/kg food

Assessment factor:

90

Additional information

PNECs

The PNECs for the different compartment can be calculated either by application an assessment factor (PNECfreshwater, PNECmarine water, PNECintermittent release and PNECstp) or using the equilibrium assumption method (PNECsediment freshwater, PNECsediment marine water and PNECsoil). The PNECoral is not considered as relevant, however, it is calculated based on available mammalian data and for completeness. The utilized procedures are described in detail in the ECHA Guidance of May 2008, Chapter R.10 ("Guidance on information requirements and chemical safety assessment").

Classification and Labelling

Most critical parameter was obtained by the conducted experiment with Pseudomonas subcapitata according to OECD 201 (Nierzedska, 2009). The measured acute value (ErC50 after 72 h) of > 70.92 mg/L is refuted by the obtained NOEC < 9.75 mg/L in the same experiment. Furthermore, sodium [2,2'-(ethane-1,2-diylbis{[2-(hydroxy-kO)benzyl]imino-kN})diacetato-kO(4-)]ferrat(1-) (FeHBED) is not bioaccumulative (based on the substance specific logPow of -1.96, which was experimentally determined by Guzik (2012) according to OECD 107). Thereby, secondary poisoning is also considered as not relevant. The test substance is considered neither readily nor inherently biodegradable (Chojnacka, 2010).

Based on the available experimental results, Fe(Na)HBED is not classified and labelled in respect to the environmental compartment in accordance to the criteria given in Directive 67/548/EC and Regulation (EC) 1272/2008.

General considerations for the test substance

Sodium [2,2'-(ethane-1,2-diylbis{[2-(hydroxy-kO)benzyl]imino-kN})diacetato-kO(4-)]ferrat(1-) (Fe(Na)HBED) is used in alkaline soils (pH > 7.5) to act as iron donor and thus to supply plants with this micronutrient. In high pH soils, nutrients (i.e. iron) solve inferior and are not available in an adequate manner for different plants and may lead to deficiency symptoms like chlorosis. The coenzym nicotinamide adenine dinucleotide phosphate (NADP+/HADPH) is involved in the uptake of iron via the complexing agent HBED in dicotyledonous plants by reducing Fe3+ in the complex to Fe2+ which is then taken up into the root cell. The chelating agent receives a H+ ion from the coenzyme and diffuses back to the soil solution, remaining around the Rhizosphere in order to gather another native iron cation from the soil compartment. Some grass roots take up the entire complex into the root cells. Then the Fe3+ is reduced to Fe2+, which is not able to leave the cell again, while the chelating agent is passed back into the soil solution.

Conclusion on classification

Sodium [2,2'-(ethane-1,2-diylbis{[2-(hydroxy-kO)benzyl]imino-kN})diacetato-kO(4-)]ferrat(1-) (FeHBED) has not to be classified and labelled according to Directive 67/548/EC and Regulation (EC) No 1272/2008 of the European Parliament and the Council.