Ferrate(1-), [[N,N'-1,2-ethanediylbis[N-[[2-(hydroxy-.kappa.O)phenyl]methyl]glycinato-.kappa.N,.kappa.O]](4-)]-, sodium (1:1), (OC-6-13)-

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: GLP study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

GLP compliance:

yes

Remarks:

G-013

Type of method:

flask method

Water solubility:

34.55 g/L

Temp.:

20 °C

pH:

5.4

Remarks on result:

other: in distilled water

Water solubility:

15.68 g/L

Temp.:

20 °C

pH:

4

Remarks on result:

other: in buffer solution

Water solubility:

18.02 g/L

Temp.:

20 °C

pH:

7

Remarks on result:

other: in buffer solution

Water solubility:

28.45 g/L

Temp.:

20 °C

pH:

10

Remarks on result:

other: in buffer solution

Solubility of the Chelat Fe(III) HBED in water for pH 5.4; flask method

 

 

Results of the preliminary test

0.1g in x mL of solution Result	0.1	0.5	1	2	10	100	> 100
Soluble (+/-)	-	-	-	-	+
Approximate solubility, [g/L]	> 1000	200 to 1000	100 to 200	50 to 100	10 to 50	1 to 10	< 1

x – distilled water.

 

 

Solubility results Chelat Fe(III) HBED in water for pH 5.4

Mixing time [hours]		72	118	142
1 flask	Concentration Chelat Fe(III) HBED, [g/L]	34.31	34.48	35.23
	pH	7.40	7.41	7.40
2 flask	Concentration Chelat Fe(III) HBED, [g/L]	34.23	34.71	34.07
	pH	7.43	7.41	7.43
3 flask	Concentration Chelat Fe(III) HBED, [g/L]	34.28	34.46	35.23
	pH	7.40	7.43	7.43
Average concentration Chelat Fe(III) HBED, [g/L]		34.27	34.55	34.84
Temperature [°C]		20.03	20.03	20.03

 

Conclusions:

Interpretation of results (migrated information): very soluble (> 10000 mg/L)
Water solubility of test substance as a function of pH at 20 ±0.5°C:
34.55 g/L with distilled water at pH 5.4;
15.68 g/L with buffer solution at pH 4.0;
18.02 g/L with buffer solution at pH 7.0;
28.45 g/L with buffer solution at pH 10.0.

Executive summary:

The water solubility of the test substance was determined in a GLP study (2009) according to EU method A.6 by using the flask method. At 20°C following results for the water solubility as a function of pH have been obtained:

34.55 g/L with distilled water at pH 5.4;

15.68 g/L with buffer solution at pH 4.0;

18.02 g/L with buffer solution at pH 7.0;

28.45 g/L with buffer solution at pH 10.0.

Description of key information

The water solubility of the test substance was determined in a GLP study (2009) according to EU method A.6 by using the flask method. At 20°C following results for the water solubility as a function of pH have been obtained:
34.55 g/L with distilled water at pH 5.4;
15.68 g/L with buffer solution at pH 4.0;
18.02 g/L with buffer solution at pH 7.0;
28.45 g/L with buffer solution at pH 10.0.

Key value for chemical safety assessment

Water solubility:

34 550 mg/L

at the temperature of:

20 °C