Registration Dossier

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
no hazard identified

Marine water

Hazard assessment conclusion:
no hazard identified

STP

Hazard assessment conclusion:
no hazard identified

Sediment (freshwater)

Hazard assessment conclusion:
no hazard identified

Sediment (marine water)

Hazard assessment conclusion:
no hazard identified

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
no exposure of soil expected

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

According to Article 13 of Regulation (EC) No. 1907/2006 "General Requirements for Generation of Information on Intrinsic Properties of substances", Information on intrinsic properties of substances may be generated by means other than tests e.g. from information from structurally related substances (grouping or read-across), provided that conditions set out in Annex XI are met. Annex XI, "General rules for adaptation of this standard testing regime set out in Annexes VII to X” states that “substances whose physicochemical, toxicological and ecotoxicological properties are likely to be similar or follow a regular pattern as a result of structural similarity may be considered as a group, or ‘category’ of substances. This avoids the need to test every substance for every endpoint”. Since the analogue concept is applied to the target substance data will be generated from representative read-across substances to avoid unnecessary animal testing. Additionally, once the analogue concept is applied, the substance will be classified and labelled on this basis.

Partition coefficient

The log Kow is measured to be -2 (OECD 107)  

Degradation

Biodegradation: readily biodegradable: >70% in 28 days (OECD 301B)

 

Bioaccumulation

Bioaccumulation is assumed to be low based on a measured log Kow of -2.  

 

Aquatic short-term toxicity

LC50 (96h) > 500 mg/L (nominal) for Brachydanio rerio (OECD 203, limit test)

EC50 (48h) > 1000 mg/L (nominal) for Daphnia magna (OECD 202, limit test); read-across

EC50 (72h) > 1000 mg/L (nominal) for Pseudokirchnerella subcapitata (OECD 201, limit test); read-across

 

Aquatic long-term toxicity

NOEC (72h) >= 1000 mg/L (nominal) for Pseudokirchnerella subcapitata (OECD 201, limit test); read-across

 

Classification justification according to CLP:

Based on the data above, 1,2,3 -Propanetriol, homopolymer (CAS 25618-33-5) is considered to be rapidly degradable. The log Kow value is -2. The acute aquatic toxicity L(E)C50 is > 100 mg/L in water for fish, algae and daphnia. Valid chronic data are available for algae; however, no effects were observed up to 1000 mg/L. Therefore, 1,2,3 -Propanetriol, homopolymer (CAS 25618-33-5) does not need to be classified and labelled as environmental hazard according to the 2nd ATP of the Regulation (EC) No.1272/2008 (CLP).

 

Classification justification according to DSD:

Based on the data above, 1,2,3 -Propanetriol, homopolymer (CAS 25618-33-5) is considered to be rapidly degradable. The potential for bioaccumulation is low based on a measured log Kow of -2. The acute aquatic toxicity L(E)C50 is > 100 mg/L in water for fish, algae and daphnia. Therefore, 1,2,3 -Propanetriol, homopolymer (CAS 25618-33-5) does not need to be classified and labelled as environmental hazard according to Directive 67/548/EE.