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Regarding biodegradation of bis(2,6 -diisopropylphenyl)carbodiimide only data are available concerning water as compartment in two experiments conducted according to OECD Guideline 301 F (Weyers, 2009) and OECD Guideline 301 B (Mead, 2001). In the first study a degradation of 1 % was determined after 28 days test duration. In the second experiment, the test material attained 3 % degradation after 28 days. Based on these study results, it can be concluded that the substance is "not readily biodegradable".

Additionally, a QSAR calculation was performed to predict the biodegradability potential due to its chemical structure with the help of BIOWIN v4.10 (Chemservice S.A., 2011). It can be used as supporting data, since the overall prediction result is "not readily biodegradable", neither under aerobic nor under anaerobic conditions. Furthermore, the chemical was evaluated using the Start plug-in in Toxtree (v.2.5.0), whereby the substance is assigned to the class II - persistent chemical.

For the main hydrolytical degradation product DIPA biodegradation potential was also modelled. The prediction for biodegradability of2,6-diisopropylaniline, (CAS 24544 -04 -5) was performed again with BIOWIN v4.10 (EPIWIN software) (Chemservice S.A, 2016). According to Biowin 1 the substance is biodegrading fast, whereas Biowin 2 estimates that the compound does not biodegrade fast. The Ultimate Biodegradation Timeframe is given in weeks-months, whereas the Primary Biodegradation Timeframe gives days-weeks as result. Both MITI Models predict that the substance does not biodegrade fast. Also under anaerobic conditions the substance is not expected to be degraded fast. The overall Ready Biodegradability Prediction reveals: No.