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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 905-588-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://www.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.327 mg/L
- Assessment factor:
- 1
- Extrapolation method:
- sensitivity distribution
- PNEC freshwater (intermittent releases):
- 0.327 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.327 mg/L
- Assessment factor:
- 1
- Extrapolation method:
- sensitivity distribution
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 6.58 mg/L
- Assessment factor:
- 1
- Extrapolation method:
- sensitivity distribution
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 12.46 mg/kg sediment dw
- Assessment factor:
- 1
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 12.46 mg/kg sediment dw
- Assessment factor:
- 1
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- hazard related to composition of atmosphere identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 2.31 mg/kg soil dw
- Assessment factor:
- 1
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
PNECs were derived for freshwater, saltwater, sediment, and soil using the Petrotox model or equilibrium partitioning calculations.
The screening criteria for toxicity is that a substance with an acute EC50 or LC50 <0.1 mg/L is considered to potentially meet the T criterion, and that an EC50 or LC50 <0.01 mg/L indicates that the substance is definitely T. The criteria in Annex XIII is that a substance with a chronic EC10 / NOEC ≤ 0.01 mg/L is considered to be T. It is difficult to assess the toxicity of streams using standard test methods as the tests measure the properties of the whole substance. It is more appropriate to consider whether the representative components are toxic and therefore data have been read across from the xylene isomers and ethylbenzene.
The key short-term toxicity to fish result is a 96 hour LC50 of 2.6 mg/L for p-xylene. The key short-term toxicity to invertebrates result is a 48 hour EC50 for Daphnia magna of 3.82 mg/L for o-xylene and a 24 hour EC50 for Daphnia magna of 1 mg/L is also reported for o-xylene. The key short-term toxicity to algae result is a 72 hour ErC50 of 3.2 mg/L for p-xylene and a 48 hour EC50 of 1.3 mg/L is also reported for ethylbenzene. The key long-term toxicity to fish result is a 56 day NOEC of 1.3 mg/L for mixed xylenes. The key long-term toxicity to invertebrates result is a 7 day NOEC for Ceriodaphnia dubia of 0.96 mg/L for ethylbenzene. The key long-term toxicity to algae result is a 73 hour NOEC of 0.44 mg/L for p-xylene.
None of the short-term ecotoxicity results for the xylene isomers or ethylbenzene are less than 1 mg/L and none of the lowest long-term ecotoxicity results are less than 0.1 mg/L. Therefore, based on the screening criteria for environmental toxicity stipulated in the ECHA's Guidance on information requirements and chemical safety assessment [Part C: PBT Assessment (2008)] the toxicity criteria are not met. Therefore, the category members are not considered to be T on the basis of these criteria.
Conclusion on classification
The key short-term toxicity to fish result is a 96 hour LC50 of 2.6 mg/L for p-xylene. The key long-term toxicity to fish result is a 56 day NOEC of 1.3 mg/L for mixed xylenes.
The key short-term toxicity to invertebrates result is a 48 hour EC50 for Daphnia magna of 3.82 mg/L for o-xylene. A 24 hour EC50 for Daphnia magna of 1 mg/L is also reported for o-xylene but both this and the key study (48 hour EC50 of 3.82 mg/L) with the same test organism are considered valid. None of the results for short-term toxicity to invertebrates for the xylene isomers or ethylbenzene are less than 1 mg/L. The key long-term toxicity to invertebrates result is a 7 day NOEC for Ceriodaphnia dubia of 0.96 mg/L for ethylbenzene.
The key short-term toxicity to algae result is a 72 hour ErC50 of 3.2 mg/L for p-xylene. A 48 hour EC50 of 1.3 mg/L is also reported for ethylbenzene in the Draft Screening Assessment Report by Environment Canada (2014). None of the results for short-term toxicity to algae for the xylene isomers or ethylbenzene are less than 1 mg/L. The key long-term toxicity to algae result is a 73 hour NOEC of 0.44 mg/L for p-xylene.
None of the short-term ecotoxicity results for the xylene isomers or ethylbenzene are less than 1 mg/L. The lowest long-term ecotoxicity results for the xylene isomers and ethylbenzene are between 0.1 and 1 mg/L. Data on the xylene isomers and ethylbenzene indicates that biodegradation is rapid and that they will partition to the air from water, further reducing their potential for exposure. An experimentally determined BCF for mixed xylenes in fish gave a result of 29, indicating a low potential for bioaccumulation.
These values confirmed that a classification for acute hazard to the environment is not required but a Chronic Category 3 classification is required under the CLP Regulations and this has been added as a self classification to the dossier.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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