Registration Dossier
Registration Dossier
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EC number: 701-005-7 | CAS number: -
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline Study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 998
- Report date:
- 1988
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- ISO 8192 (Water quality - Test for inhibition of oxygen consumption by activated sludge for carbonaceous and ammonium oxidation)
- GLP compliance:
- no
Test material
- Reference substance name:
- Isotridecan-1-ol
- EC Number:
- 248-469-2
- EC Name:
- Isotridecan-1-ol
- Cas Number:
- 27458-92-0
- Molecular formula:
- C13H28O
- IUPAC Name:
- Isotridecanol (reaction product of dodecene)
- Details on test material:
- - Name of test material (as cited in study report): Tridecanol N (Isotridecanol)
- Analytical purity: not reported
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test organisms
- Test organisms (species):
- activated sludge, domestic
- Details on inoculum:
- - Laboratory culture: activated sludge from a municipal sewage treatment plant (Lambsheim, Germany)
- Initial biomass concentration: 1 g/L
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 30 min
Test conditions
- Details on test conditions:
- Total test volume: 250 ml containing 260 mg test substance (1040 mg/L, TOC = 811 mg/g, 50 ml inoculum (5 g/L), 8 ml medium
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 30 min
- Dose descriptor:
- other: EC20
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Duration:
- 30 min
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Duration:
- 30 min
- Dose descriptor:
- other: EC80
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
Any other information on results incl. tables
No inhibition of respiration was observed after incubation of 1040 mg/l for 30 min, at the concentration of 1040 mg/l.
Applicant's summary and conclusion
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