Registration Dossier
Registration Dossier
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EC number: 701-005-7 | CAS number: -
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: peer reviewed publication
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Higher alcohols bioconcentration: Influence of biotransformation
- Author:
- De Wolf W, Parkerton TF
- Year:
- 1 999
- Bibliographic source:
- Extended Abstracts of the 217th ACS National Meeting, Anaheim, CA, Symposium "Persistent, Bioaccumulative, Toxic Chemicals, March 21-25, 1999
- Report date:
- 1999
- Reference Type:
- secondary source
- Title:
- SIDS Initial Assessment Report for SIAM 22
- Author:
- OECD SIAM 22
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 305 (Bioconcentration: Flow-through Fish Test)
- GLP compliance:
- no
Test material
- Details on test material:
- Branched commercial alcohols with chain-lengths of C10, C12 and C13 carbons
Constituent 1
Test organisms
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- TEST ORGANISM
- Common name: rainbow trout
- Age at study initiation: juvenile
- Weight at study initiation: 0.2 - 0.9 g
- Lipid content: 3.5 - 5.8%
Study design
- Route of exposure:
- aqueous
- Test type:
- flow-through
- Water / sediment media type:
- natural water: freshwater
- Total exposure / uptake duration:
- 10 d
- Total depuration duration:
- 4 d
Results and discussion
Bioaccumulation factor
- Type:
- BCF
- Value:
- < 100
- Details on results:
- - Uptake phase: fish attained rapidly a steady-state concentration of alcohols
- Rapid elimination occurred after transfer to clean water
Applicant's summary and conclusion
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