Registration Dossier

Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: peer reviewed publication

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Higher alcohols bioconcentration: Influence of biotransformation
Author:
De Wolf W, Parkerton TF
Year:
1999
Bibliographic source:
Extended Abstracts of the 217th ACS National Meeting, Anaheim, CA, Symposium "Persistent, Bioaccumulative, Toxic Chemicals, March 21-25, 1999
Report Date:
1999
Reference Type:
secondary source
Title:
SIDS Initial Assessment Report for SIAM 22
Author:
OECD SIAM 22
Year:
2006
Report Date:
2006

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 305 (Bioconcentration: Flow-through Fish Test)
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Branched commercial alcohols with chain-lengths of C10, C12 and C13 carbons

Test organisms

Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)
Details on test organisms:
TEST ORGANISM
- Common name: rainbow trout
- Age at study initiation: juvenile
- Weight at study initiation: 0.2 - 0.9 g
- Lipid content: 3.5 - 5.8%

Study design

Route of exposure:
aqueous
Test type:
flow-through
Water / sediment media type:
natural water: freshwater
Total exposure / uptake duration:
10 d
Total depuration duration:
4 d

Results and discussion

Bioaccumulation factor
Type:
BCF
Value:
< 100
Details on results:
- Uptake phase: fish attained rapidly a steady-state concentration of alcohols
- Rapid elimination occurred after transfer to clean water

Applicant's summary and conclusion