Registration Dossier
Registration Dossier
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EC number: 939-703-0 | CAS number: 1474044-75-1
Endpoint summary
Administrative data
Description of key information
Additional information
In a 96-h acute toxicity study, zebra fish were exposed to the test item at nominal concentrations of 0 (control) 32, 58, 100, 180, 320, 580 and 1000 mg/L under static conditions. The LC50 was calculated as 134.2 mg/L. The LC0 was graphically determined as 100 mg/L. The test item is not acutely toxic to fish, but in the range of solubility of the test item.
The 48–hr-acute toxicity of the test item to Daphnia magna was studied under static conditions. Daphnids were exposed to control and test item at nominal concentration of 32, 58, 100, 180 and 320 mg/L for 48 hr. The 48–hr EC50 was 83 mg/L. The 48–hr EC0 based on immobilization was 32 mg/L.
Two studies with green algae were conducted. The key study is an OECD 201 guideline compliant study conducted with Desmodesmus subspicatus over 72 hours. After 72 hours the EC50 values for inhibition of growth rate and yield were 29 and 16.7 mg/L, respectively. The EC10 values for inhibition of growth rate and yield were 16.5 and 11.7 mg/L, respectively. All validity criteria were met.
In a non-GLP supporting study over 5 days with the green algae Desmodesmus subspicatus, formerly known as Scenedesmus subspicatus, the EC50 for growth rate was graphically determined to be 47 mg/L.
In a 3-hr acute toxicity study sewage sludge microorganisms were exposed to the test item at nominal concentrations of 0, 12.3, 37, 111, 333 and 1000 mg/L in accordance with OECD 209. The EC50 value based on respiration rate after 3 hours was 100 mg/L.
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