Registration Dossier

Diss Factsheets

Administrative data

Description of key information

1,2,4 -benzenetricarboxylic acid, mixed dodecyl and octyl triesters is expected to be only slightly irritating when applied to rabbit skin and does not cause irritation when applied to rabbit eyes (derived from read-across).

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

The skin and eye irritation properties of 1,2,4 -benzenetricarboxylic acid, mixed dodecyl and octyl triesters were not specifically determined. However, data are available for a structurally related material (1,2,4-Benzenetricarboxylic acid, decyl octyl ester), the only difference being the presence of esters with a shorter alkyl chain (C10 instead of C12). The available information demonstrates only slight irritating effects on rabbit skin and no irritating effects in rabbit eyes.

Effects on skin irritation/corrosion: slightly irritating

Justification for classification or non-classification

No classification for skin or eye irritation or corrosion is indicated according to the general classification and labeling requirements for dangerous substances and preparations (67/544 EEC) or the classification, labeling and packaging (CLP) regulation (EC 1272/2008).