Registration Dossier
Registration Dossier
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EC number: 212-783-8 | CAS number: 868-85-9
Endpoint summary
Administrative data
Description of key information
Additional information
Concerning the toxicity of dimethyl phosphonate towards aquatic species, experimental results of short term tests on each trophic level are available. During aquatic ecotoxicity tests dimethyl phosphonate hydrolysed with half lives of several minutes to hours. Thus, during these tests, dimethyl phosphonate itself and its degradation products monomethyl phosphonate, methanol, and phosphonic acid were present.
For fish and algae no toxic effect could be determined up to a nominal dimethyl phosphonate concentration of 100 mg/L (Bayer AG, 1992 and Bayer AG, 2003). Also the respiration rate of activated sludge was not inhibited up to a nominal dimethyl phosphonate concentration of 100 mg/L (Bayer AG, 1992). Only at a higher concentration of 1000 mg/L respiration was inhibited by 7%.
The most critical effect was found on Daphnia magna (Bayer AG, 2003). In a GLP study according to EU Method C.2 a nominal EC50 of 24.8 mg/L was found after a 48 h exposure period. Analytical monitoring during the test revealed significant concentrations of monomethyl phosphonate at any nominal dimethyl phosphonate concentration (22-35% w/w of initial dimethyl phosphonate). While monomethyl phosphonate remained in solution dimethyl phosphonate was not detectable after 48 h.
Tests on long-term toxicity are not available.
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