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Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
No information
Year:
1967
Bibliographic source:
Industrial Hygiene Foundation of America, Chemical and Toxicological Series, Bulletin. (Pittsburgh, PA) 1947-69. v. 6, p. 1, 1967 (RTECS Database)
Reference Type:
review article or handbook
Title:
No information
Year:
1992
Bibliographic source:
R.J. Lewis, sr., Sax´s Dangerous Properties of Industrial Materials, Eighth Edition, 1992
Reference Type:
review article or handbook
Title:
No information
Year:
1988
Bibliographic source:
Lenga, R.E., The Sigma-Aldrich Library of Chemical Safety Data, ed.II, vol.1, 1988

Materials and methods

Principles of method if other than guideline:
Database entry, method not known.
GLP compliance:
not specified
Test type:
standard acute method

Test material

Constituent 1
Chemical structure
Reference substance name:
Isopropyl chloroformate
EC Number:
203-563-2
EC Name:
Isopropyl chloroformate
Cas Number:
108-23-6
Molecular formula:
C4H7ClO2
IUPAC Name:
propan-2-yl carbonochloridate

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
11 300 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU