Registration Dossier
Registration Dossier
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EC number: 201-696-0 | CAS number: 86-74-8
Endpoint summary
Administrative data
Description of key information
Additional information
Bioaccumulation aquatic / sediment
In a valid flow-through bioaccumulation experiment with carp according to OECD test guideline 305 C (May 12,1981), steady state BCF values of 241 and 200 were determined for aqueous carbazole exposure levels of 0.05 and 0.005 mg/L, respectively (NITE/CERI 2002/1999).
In two static bioaccumulation experiments using guppy (48 h) and daphnia (24 h), dynamic BCF were obtained using uptake and depuration rate constants determined from the aqueous concentration-time course (de Voogt 1991) and from the concentration time course in test solution and in test animals (daphnia, Southworth 1979). The dynamic BCF values observed were 500 and 115, respectively.
For the experiment with daphnia, differences between elimination rate constants obtained by the bioaccumulation experiment and by an independent depuration experiment indicate that the model used does not fit well the bioaccumulation of carbazole in the test animals.
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