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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

The 48 hr LC50/EC50 values for Daphnia magna exposed to the four main components of the reaction mass, n-hexane (CAS No. 110-54-3), cyclohexane (CAS No. 110-82-7), Toluene (CAS No. 108-88-3) and 4-vinylcyclohexene (CAS No. 100-40-3), ranged from 0.90 mg/L to 3.78 mg/L.

Key value for chemical safety assessment

Additional information

Reliable experimental studies were available for two of the main components of the reaction mass, cyclohexane (Adam et al, 1987: 48 hr EC50 0.9 mg/L) and toluene (Niederlehner et al,1998: 48 hr LC50 3.78 mg/L).

In the absence of reliable experimental studies the short term toxicity to aquatic invertebrates for the two remaining main components, were predicted using the QSAR model ECOWIN v1 ECOSAR Classes for Microsoft Windows. The model predicted 48 hr LC50 values of 3.33 mg/L for n-hexane and 1.81 mg/L for 4-vinylcyclohexene.