Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-851-8 | CAS number: 111-26-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
In a 96 h static procedure the LC50 of the test substance to fish was determined to be 14.7 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 14.7 mg/L
Additional information
A study was conducted on the golden orfe (Leuciscus idus) to assess the acute toxicity of n-hexylamine. The substance was tested in a static 96 h- procedure. The nominal concentrations were 10, 21.5, 46.4 and 100 mg/L. 10 fish were used per aquarium and per concentration. The LC50 (96 h) was determined to be 14.7 mg/L. No mortality and no symptoms were observed in an additional test solution (100 mg/L), which was pH-adjusted, resulting in an LC50 (96 h) of >100 mg/L based on the pH-adjusted test solution.
In a publication (Geiger et al. 1986) another 96 hours static toxicity test on fish is described which was conducted on fathead minnows (Pimephales promelas). The nominal test concentrations were 0, 13.2, 20.3, 31.3, 48.1, 74 mg/L (measured 12.3, 18.9, 29, 43.9, 66.4 mg/L). Deaths occurred from the 48.1 mg/L group onwards. Behavioural abnormalities were loss of schooling behavior, hypoactivity and loss of equilibrium, also observed in the 48.1 and 74 mg/L groups. Based on these results the LC50 (96 h) as well as the EC50 (96 h) values were determined to be 56.6 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
