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Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008-05-26 to 2008-07-09
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP, guideline study
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
, 1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
, 1992
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
signed 2004-09-06
Type of method:
thermal analysis
Remarks:
DSC

Test material

Constituent 1
Chemical structure
Reference substance name:
1-(4-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-2,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)propan-1-one
EC Number:
700-320-7
Cas Number:
18916-17-1
Molecular formula:
C27H34O14
IUPAC Name:
1-(4-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-2,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)propan-1-one
Constituent 2
Reference substance name:
1-[4-[[2-O-(6-Deoxy-L-mannopyranosyl)-D-glucopyranosyl]oxy]-2,6-dihdroxyphenyl]-3(4-hydroxyphenyl)-1-propanone
IUPAC Name:
1-[4-[[2-O-(6-Deoxy-L-mannopyranosyl)-D-glucopyranosyl]oxy]-2,6-dihdroxyphenyl]-3(4-hydroxyphenyl)-1-propanone
Details on test material:
- Name of test material (as cited in study report): Naringin dihydrochalcone (DHC)
- Substance type: technical product
- Physical state: whitish powder
- Storage condition of test material: 15 – 25 °C, dark and dry
No further details are given.

Results and discussion

Melting / freezing point
Decomposition:
yes
Decomp. temp.:
ca. 160 °C
Remarks on result:
other: The test item had no melting point at atmospheric condition.

Applicant's summary and conclusion

Conclusions:
The test item had no melting point at atmospheric condition. The decomposition of the test item started at approx. 160°C.