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EC number: 700-320-7 | CAS number: 18916-17-1
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2008-05-26 to 2008-06-10
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP, guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 008
- Report date:
- 2008
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
- Version / remarks:
- , 1981
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 187: Particle Size Analysis by Laser Diffraction
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: ISO13320-1: Particle Size Analysis - Laser Diffraction Methods
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- signed 2004-09-06
- Type of distribution:
- volumetric distribution
Test material
- Reference substance name:
- 1-(4-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-2,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)propan-1-one
- EC Number:
- 700-320-7
- Cas Number:
- 18916-17-1
- Molecular formula:
- C27H34O14
- IUPAC Name:
- 1-(4-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-2,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)propan-1-one
- Reference substance name:
- 1-[4-[[2-O-(6-Deoxy-L-mannopyranosyl)-D-glucopyranosyl]oxy]-2,6-dihdroxyphenyl]-3(4-hydroxyphenyl)-1-propanone
- IUPAC Name:
- 1-[4-[[2-O-(6-Deoxy-L-mannopyranosyl)-D-glucopyranosyl]oxy]-2,6-dihdroxyphenyl]-3(4-hydroxyphenyl)-1-propanone
- Details on test material:
- - Name of test material (as cited in study report): Naringin dihydrochalcone (DHC)
- Substance type: technical product
- Physical state: whitish powder
- Storage condition of test material: 15 – 25 °C, dark, dry, don’t freeze, keep away from strong light and heat
No further details are given.
Constituent 1
Constituent 2
Results and discussion
Particle sizeopen allclose all
- Percentile:
- D50
- Mean:
- 10 µm
- Remarks on result:
- other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
- Percentile:
- D50
- Mean:
- 10 µm
- St. dev.:
- 0.08
- Percentile:
- D10
- Mean:
- 2.4 µm
- St. dev.:
- 0.04
- Percentile:
- D90
- Mean:
- 40.2 µm
- St. dev.:
- 0.54
Particle size distribution at different passagesopen allclose all
- No.:
- #1
- Size:
- 0.02 µm
- Distribution:
- 0 %
- No.:
- #2
- Size:
- 356 µm
- Distribution:
- 100 %
- No.:
- #5
- Size:
- 5.6 µm
- Distribution:
- 26 %
- No.:
- #3
- Size:
- 0.6 µm
- Distribution:
- 2.8 %
- No.:
- #4
- Size:
- 1 µm
- Distribution:
- 5 %
- No.:
- #6
- Size:
- 8.9 µm
- Distribution:
- 44 %
- No.:
- #7
- Size:
- 12.6 µm
- Distribution:
- 60 %
- No.:
- #8
- Size:
- 20 µm
- Distribution:
- 76.7 %
- No.:
- #9
- Size:
- 79.6 µm
- Distribution:
- 95.8 %
- No.:
- #10
- Size:
- 126.2
- Distribution:
- 97.7 %
Applicant's summary and conclusion
- Conclusions:
- The average of the median physical particle size D50 is 10 µm.
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