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Administrative data

Endpoint:
surface tension
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008-07-28 to 2008-07-30
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP, guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 115 (Surface Tension of Aqueous Solutions)
Version / remarks:
, 1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.5 (Surface Tension)
Version / remarks:
, 1992
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
signed 2006-06-01
Type of method:
OECD harmonised ring method

Test material

Constituent 1
Chemical structure
Reference substance name:
1-(4-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-2,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)propan-1-one
EC Number:
700-320-7
Cas Number:
18916-17-1
Molecular formula:
C27H34O14
IUPAC Name:
1-(4-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-2,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)propan-1-one
Constituent 2
Reference substance name:
1-[4-[[2-O-(6-Deoxy-L-mannopyranosyl)-D-glucopyranosyl]oxy]-2,6-dihdroxyphenyl]-3(4-hydroxyphenyl)-1-propanone
IUPAC Name:
1-[4-[[2-O-(6-Deoxy-L-mannopyranosyl)-D-glucopyranosyl]oxy]-2,6-dihdroxyphenyl]-3(4-hydroxyphenyl)-1-propanone
Details on test material:
- Name of test material (as cited in study report): Naringin dihydrochalcone (DHC)
- Substance type: technical product
- Physical state: whitish powder
- Storage condition of test material: room temperature, protected from moisture and light
No further details are given.

Results and discussion

Surface tension
Surface tension:
65.65 mN/m
Temp.:
20 °C
Conc.:
90 other: % saturated solution

Any other information on results incl. tables

Table 1: Measured surface tension and temperature

Measurement No.*

Time** (minutes)

Surface tension (mN/m)

Temperature (°C)

1

6.6

65.69

20.0

2

7.3

65.67

20.0

3

8.1

65.64

20.0

4

8.9

65.65

20.0

5

9.6

65.65

20.0

6

10.4

65.65

20.0

7

11.2

65.65

20.0

8

11.9

65.65

20.1

9

12.7

65.62

20.1

10

13.5

65.63

20.1

Mean

-

65.65

20.03

SD

-

0.02

0.05

* last 10 measurements; ** time from transfer of the test solution into the vessel till end of each measurement

Applicant's summary and conclusion

Conclusions:
The surface tension of a 90% saturated aqueous solution of the test item was determined to be 65.65 mN/m. Due to the fact that the surface tension is > 60mN/m, the test item has no surface-active properties.