Registration Dossier
Registration Dossier
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EC number: 305-769-9 | CAS number: 95009-41-9
Endpoint summary
Administrative data
Description of key information
Additional information
Fatty acids, vegetable-oil, esters with dipropylene glycol (CAS 95009-41-9) is determined to be readily biodegradable in one experimental study (84.1% after 28 d, OECD 301B). Hence, abiotic degradation is not a relevant pathway in the environment.
Based on its physico-chemical properties such as low water solubility (<0.01 mg/L at 20 °C, pH=5.82 - 5.92), low volatilization potential (vapour pressure: < 0.0001 Pa at 20 °C) and high log Koc (> 3), sediment and soil are expected to be the main targets for environmental distribution of the substance. However, due to its ready biodegradability, the substance will not persist in these compartments if exposure occurs.
Moreover, due to the low water solubility, rapid environmental biodegradation and metabolisation via enzymatic hydrolysis, a relevant uptake and bioaccumulation in aquatic organisms is not expected. Glycol esters have a common metabolic fate that involves a stepwise hydrolysis of the ester bonds by gastrointestinal enzymes by which the breakdown of glycol esters results in structurally similar chemicals, the fatty acid component and the respective alcohol (Long, 1958; Lehninger, 1970; Mattson and Volpenhein, 1972). Following hydrolysis of the ester bond, the breakdown product will be absorbed and metabolised. The toxicological properties show that the substance has a similar toxicokinetic behavior.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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