3,5-dichloronitrobenzene

Long-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

long-term toxicity to aquatic invertebrates

Type of information:

migrated information: read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Datas from isomer.

Data source

Reference

Reference 1

Reference Type:

publication

Title:

1,3-Dichlor-4-nitrobenzol

Author:

Beratergremium Umweltrelevanter Altstoffe

Year:

1991

Bibliographic source:

BUA Stoffbericht 64, VCH Weinheim

Reference 2

Reference Type:

publication

Title:

QSAR Study of the toxicity of nitrobenzene derivatives towards daphnia magna, chlorelle pyrenoidosa and photobacterium phosphoreum

Author:

Deneer et. al.

Year:

1989

Bibliographic source:

Aquat toxicol. 15, 83-89

Materials and methods

Test guideline

Guideline:

EU Method C.20 (Daphnia magna Reproduction Test)

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

1,3-dichloro-4-nitrobenzene

EC Number:

210-248-3

EC Name:

1,3-dichloro-4-nitrobenzene

Cas Number:

611-06-3

IUPAC Name:

2,4-dichloro-1-nitrobenzene

Test organisms

Test organisms (species):

Daphnia magna

Study design

Test type:

semi-static

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

21 d

Dose descriptor:

EC50

Effect conc.:

4.4 mg/L

Nominal / measured:

not specified

Conc. based on:

test mat.

Basis for effect:

immobilisation

Effect concentrations 2

Duration:

21 d

Dose descriptor:

LOEC

Effect conc.:

1 mg/L

Nominal / measured:

not specified

Conc. based on:

test mat.

Basis for effect:

reproduction

Effect concentrations 3

Duration:

21 d

Dose descriptor:

LOEC

Effect conc.:

3.2 mg/L

Nominal / measured:

not specified

Conc. based on:

test mat.

Basis for effect:

growth