Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
secondary source
Title:
IUCLID DATAFILE
Author:
unknown
Year:
2000
Bibliographic source:
Esis-Database, European Chemicals Bureau

Materials and methods

Test guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
GLP compliance:
no
Test type:
acute toxic class method

Test material

Constituent 1
Chemical structure
Reference substance name:
3,5-dichloronitrobenzene
EC Number:
210-557-3
EC Name:
3,5-dichloronitrobenzene
Cas Number:
618-62-2
Molecular formula:
C6H3Cl2NO2
IUPAC Name:
3,5-dichloronitrobenzene

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
peanut oil
Doses:
250, 500, 1000 mg/kg
No. of animals per sex per dose:
4

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
390 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU