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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
secondary source
Title:
IUCLID DATAFILE
Author:
unknown
Year:
2000
Bibliographic source:
Esis-Database, European Chemicals Bureau

Materials and methods

Test guideline
Guideline:
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3,5-dichloronitrobenzene
EC Number:
210-557-3
EC Name:
3,5-dichloronitrobenzene
Cas Number:
618-62-2
Molecular formula:
C6H3Cl2NO2
IUPAC Name:
1,3-dichloro-5-nitrobenzene

Test animals

Species:
rabbit
Strain:
New Zealand White

Test system

Type of coverage:
occlusive
Preparation of test site:
other: clipped and scarified
Vehicle:
unchanged (no vehicle)
Duration of treatment / exposure:
24
Observation period:
72
Number of animals:
4

Results and discussion

Any other information on results incl. tables

No irritation was observed after 24 and 72 hours.

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU