Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Datas from isomer.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
1,3-Dichlor-4-nitrobenzol
Author:
Beratergremium Umweltrelevanter Altstoffe
Year:
1991
Bibliographic source:
BUA Stoffbericht 64, VCH Weinheim
Reference Type:
publication
Title:
Quantitative structure-activity relationships for the toxicity and bioconcentration factor of nitrobenzene derivatives towards the guppy
Author:
Deneer et. al.
Year:
1987
Bibliographic source:
Aquat. Toxicol. 10, 115-129

Materials and methods

Test guideline
Guideline:
EU Method C.1 (Acute Toxicity for Fish)
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
1,3-dichloro-4-nitrobenzene
EC Number:
210-248-3
EC Name:
1,3-dichloro-4-nitrobenzene
Cas Number:
611-06-3
IUPAC Name:
2,4-dichloro-1-nitrobenzene

Sampling and analysis

Analytical monitoring:
not specified

Test organisms

Test organisms (species):
Poecilia reticulata

Study design

Test type:
semi-static
Water media type:
freshwater
Total exposure duration:
14 d

Test conditions

Test temperature:
21-23°C
pH:
6.8-7.2

Results and discussion

Effect concentrations
Duration:
14 d
Dose descriptor:
LC50
Effect conc.:
6.6 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
mortality (fish)

Applicant's summary and conclusion