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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study, basic data given acceptable for assessment

Data source

Reference
Reference Type:
publication
Title:
Fish test
Author:
MOE (Ministry of the Environment in Japan )
Year:
1998
Bibliographic source:
Ministry of the Environment in Japan (http://www.env.go.jp/chemi/sesaku/02e.pdf)

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
4-isopropylaniline
EC Number:
202-797-2
EC Name:
4-isopropylaniline
Cas Number:
99-88-7
Molecular formula:
C9H13N
IUPAC Name:
4-(propan-2-yl)aniline

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Oryzias latipes

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
46 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
mortality (fish)

Applicant's summary and conclusion

Executive summary:

The LC50 (96h Oryzias latipes) of 4-isopropylaniline is 46mg/L. The study followed the OECD guideline 203.