Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The long-term toxicity to fish of the read across substance didecyldimethylammonium chloride (CAS 7173 -51 -5) was determined in the OECD guideline 210 and GLP study. The NOEC was determined to be 32 µg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 32 µg/L
Additional information
A read across approach was applied for short-term toxicity to algae using data of didecyldimethylammonium chloride (CAS 7173 -51 -5) as this substance was considered to show similar ecotoxicological properties as compared to the test substance.
A 34d Early life stage test on Brachydanio rerio is available as read across data with didecyldimethylammonium chloride (CAS 7173 -51 -5). The test was carried out according to OECD Guideline No. 210 and under GLP conditions using the read across substance in 51.4 % aqueous solution and as radiolabelled 14C substance under intermittent flow-through conditions. Four replicates of 20 eggs/larvae were dosed per concentration. Nominal test concentrations were 0, 1.0, 3.2, 10, 32, 100 and 320 (active ingredient) µg /L and the results of their analytical check permitted to express the results in terms of nominal concentrations. All fish died at a test substance concentration of 320 µg /L. The test substance did not affect body length, but body weight increased at 100 µg/L. In conclusion the read across substance showed a LC50 value of 81 µg/L (active ingredient). The NOEC was determined to be 32 µg /L (active ingredient). No metabolites were formed during the test.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
