Registration Dossier

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The long-term toxicity to fish of the read across substance didecyldimethylammonium chloride (CAS 7173 -51 -5) was determined in the OECD guideline 210 and GLP study. The NOEC was determined to be 32 µg/L. 

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
32 µg/L

Additional information

A read across approach was applied for short-term toxicity to algae using data of didecyldimethylammonium chloride (CAS 7173 -51 -5) as this substance was considered to show similar ecotoxicological properties as compared to the test substance.

A 34d Early life stage test on Brachydanio rerio is available as read across data with didecyldimethylammonium chloride (CAS 7173 -51 -5). The test was carried out according to OECD Guideline No. 210 and under GLP conditions using the read across substance in 51.4 % aqueous solution and as radiolabelled 14C substance under intermittent flow-through conditions. Four replicates of 20 eggs/larvae were dosed per concentration. Nominal test concentrations were 0, 1.0, 3.2, 10, 32, 100 and 320 (active ingredient) µg /L and the results of their analytical check permitted to express the results in terms of nominal concentrations. All fish died at a test substance concentration of 320 µg /L. The test substance did not affect body length, but body weight increased at 100 µg/L. In conclusion the read across substance showed a LC50 value of 81 µg/L (active ingredient). The NOEC was determined to be 32 µg /L (active ingredient). No metabolites were formed during the test.