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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

No studies have been conducted on the reaction mass of CaF2, CaSO4 and CaCO3. Instead information is available on the 3 different constituents. 


No short-term toxicity has been observed for CaSO4 and CaCO3.





No studies are available for calcium fluoride. Available studies on NaF were used as read-across source in a weight-of-evidence approach. The chosen key value for freshwater invertebrated was the lowest reported EC50 among all the evaluated studies reported by Pearcy et al. 2015 on Hyalella azteca after 96h exposure to NaF. The EC50 was 24.8 mg/L F- which converts in 50.94 mg/L CaF2. Effects to marine invertebrates (Mysidopsis bahia) have been reported with an EC50 of 21.6 mg/L CaF2 (EU RAR). 


On the basis of the available EC50 for CaF2, the EC50 value for the reaction mass can be concluded: 101.88 mg RM/L for freshwater invertebrates and 43.2 mg/L for marine invertebrates. This value is calculated by taking into account that the reaction mass contains only 50% of CaF2 (ca. 47.5 w/w % CaF2) and that the additional of Ca2+ through CaSO4 and CaCO3 would even further reduce the toxicity of CaF2 as free F- will be complexed.




Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Dose descriptor:
EC50
Effect concentration:
101.88 mg/L

Marine water invertebrates

Marine water invertebrates
Dose descriptor:
EC50
Effect concentration:
43.2 mg/L

Additional information