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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
17 February 2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
Laser scattering/diffraction
Type of particle tested:
other:
Mass median aerodynamic diameter:
ca. 10 µm
Key result
Percentile:
D10
Mean:
4.712 µm
Remarks on result:
other: no information about standard deviation
Key result
Percentile:
D50
Mean:
10.636 µm
Remarks on result:
other: no information about standard deviation
Key result
Percentile:
D90
Mean:
32.322 µm
Remarks on result:
other: no information about standard deviation
Conclusions:
The D(0,5) of the test substance is 10,6 µm.
The D(0.9) of the test substance is 32,322 µm
The D(0.1) of the test substance is 4,712 µm

Description of key information

THe d(0,5) of the test substance is : 10.6 µm, while d(0,9) is 32,2 µm and D(0.1) =4,7 µm

Additional information

The particle size of the test item was determined by Laser diffraction particle method. Water was used a dispersant in order to obtain test substance solution at 0.0139% (vol).

Before solulisation in water, the test substance is a white to grau granular solid with some powder formation during handling and storage.