Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

The reaction mass of calcium fluoride, calcium sulfate and calcium carbonate is an inorganic substance. The soluble constituents will dissociate when dissolved in water. The ions of the substance are naturally present in the environment. The concentrations of these ions in the organism are regulated (homeostasis) and therefore no bioaccumulation is expected.

Additional information

The reaction mass of calcium fluoride, calcium sulfate and calcium carbonate is an inorganic substance.

The main constituent of the substance is calcium fluoride. A correlation between fluoride levels in earthworms and elevated soil fluoride levels from polluted sites has been demonstrated, however levels were due to the soil content of the worm gut further to ingestion rather tahn due to bioaccumulation in th tissues. Elevated fluoride content in woodlice collected from the vicinity of an Al-reduction plant has been demonstrated (Janssen et al, 1989). Sloof et al. (1989) note that uptake of fluoride into plants from soil is low as a consequence of the low bioavailability of fluoride in the soil and that atmospheric uptake is generally the most important route of exposure. A relatively high rate of fluoride uptake is noted for grass species, and the consumption of fluoride containing plants may lead to elevated fluoride levels in animals and humans. Sloof et al. (1989) conclude that the limited data indicate that fluoride biomagnification in the aquatic environment is of little significance. Fluoride accumulates in aquatic organisms predominantly in the exoskeleton of crustacea and in the skeleton of fish; no accumulation was reported for edible tissues. The EU RAR for hydrogen fluoride (2001) notes that the lowest fluoride levels are found in herbivores, with higher levels in omnivores and highest levels in predators, scavengers and pollinators; the findings indicate a moderate degree of biomagnification.Vertebrate species store most of the fluoride in the bones and (to a lesser extent) the teeth; elevated levels of fluoride in the bones and teeth have been shown in animals from polluted areas. The bioaccumulation potential of fluoride from the substance will therefore be limited by its low water solubility and its tendency to adsorb to sediment.

Regarding the 2 others constituents, calcium sulfate and calcium carbonate are inorganic ionic for which an octanol/water partition coefficient cannot be reliably determined. They

dissociate into the calcium Ca2+ , sulfate SO42- ions and carbonate CO32-ions at environmental pH. These are essential to all living organisms (flora and fauna) and their intracellular and extra-cellular concentrations are actively regulated. Bioaccumulation is thus not expected.

References :

EU RAR Hydrogen Fluoride, Volume 8, (2001)

Integrated Criteria Document Fluorides. Sloof W, Eerens HC, Janus JA & Ros RPM. (1989) National Institute of Public Health and Environmental Protection, Netherlands

Appendix to Integrated Criteria Document Fluorides. Appendix to Report 785484010, (1989) RIVM