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EC number: 806-509-1
CAS number: 1393571-42-0
Concentration (% w/w) in acetone/
olive oil 4:1
No effects on bodyweight or clinical signs, except for mild redness of
the ears at the highest concentration.
Exposure of 4 mice/ treatment during 3 consecutive days at the dorsal
site of the ears with test substance (1, 2.5 or 5%) or vehicle. On day
6, 3H-methyl thymidine(20 μCi/mouse) was injected in the tail vein. Five
hours thereafter mice were killed and draining auricular lymph nodes
were pooled per dose group and assessed for 3HTdR after 18 hours
incubation at 4°C using a Beckman LS6500 scintillation system.
At the highest dose tested the stimulation index was 5.15. The
calculated EC3 is 3%. The test substance is considered sensitizing to
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