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EC number: 806-509-1
CAS number: 1393571-42-0
Concentration (% w/w) in acetone/
olive oil 4:1
No effects on bodyweight or clinical signs, except for mild redness of
the ears at the highest concentration.
Exposure of 4 mice/ treatment during 3 consecutive days at the dorsal
site of the ears with test substance (1, 2.5 or 5%) or vehicle. On day
6, 3H-methyl thymidine(20 μCi/mouse) was injected in the tail vein. Five
hours thereafter mice were killed and draining auricular lymph nodes
were pooled per dose group and assessed for 3HTdR after 18 hours
incubation at 4°C using a Beckman LS6500 scintillation system.
At the highest dose tested the stimulation index was 5.15. The
calculated EC3 is 3%. The test substance is considered sensitizing to
In view of the low vapour pressure (2.3E-03 Pa at 25 °C) and the extreme
viscosity of the test substance, exposure via the inhalation route is
expected to negligible.
The test substance needs to be classified as a skin sensitizer: category
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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